Showing posts with label inhalation. Show all posts
Showing posts with label inhalation. Show all posts

Saturday, 4 June 2016

Routes of Entry of Hazardous Substances

Inhalation:
This is the most important route of entry as it allows the substance to directly attack lung tissue and, in some cases, to enter the blood stream and attack other organs of the body. The lungs are an active pump, drawing in air from the environment and the majority of occupational ill-­health produced by agents is caused by inhalation. Gases, such as carbon monoxide, enter the body by inhalation.




Ingestion:
occurs through the mouth. This can be accidental - such as by drinking from an unlabelled container or by poor hygiene -  eating, drinking or smoking in a contaminated environment. Respiratory defence mechanisms also push inhaled particles, such as dusts, into the throat and mouth, most of which will then be swallowed;

Absorption:
Occurs through the skin and across membranes, e.g. ammonia into the eye. Many solvents will penetrate unbroken skin and can enter the blood stream. Other substances can enter via cuts or abrasions;

Direct Entry:
Occurs through open wounds on the skin, such as dermatitis, tetanus infection and leptospirosis (Weil’s disease) from female rat urine;




Injection (skin puncture):
Caused by contact with liquids or gases under pressure or accidental puncture of the skin with contaminated sharp objects, e.g. HIV.

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Tuesday, 10 May 2016

Routes of Entry of Toxic Substance into the Body

There are four main routes of entry for the toxic chemical into the body:

INHALATION - the substance is breathed in through the nose and mouth and down into the lungs. This is a significant route of entry for many toxic substances in the form of gas, vapour, mist, fume or dust.

INGESTION - the substance is taken in through the mouth and swallowed down into the stomach and then moves on through the digestive system. Unless there is a mistaken ingestion or cross contamination, this is a less significant route of entry since people are unlikely to swallow deliberately.




ABSORPTION through the skin - the substance passes through the skin and into the tissues beneath and then into the blood stream. Only some substance such as organic solvents can permeate.

INJECTION through the skin - the substance passes through the skin barrier either by physical injection such as needle-stick injury or through damaged skin such as cuts and grazes.